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Formulation of Hair Tonic of Meniran (Phyllanthus niruri L.) Ethanol Extract as Hair Grower in Male White Rat (Rattus norvegicus) Wistar Strain


Received On: 15/09/2018
Accepted On: 21/09/2018


Author(s)

Sri Luliana, Rise Desnita, Rani Rawinda


Author's Affiliation

Dept. of Pharmacy, Medical Faculty, Tanjungpura University, Pontianak, Indonesia.


Abstract

Meniran (Phyllanthus niruri L.) has potential as a hair grower. Hair loss problems often found in various ages, both women and men. The purpose of this study was to determine the effectiveness of tonic preparations P. niruri ethanol extract as a hair grower. Tonic preparations made using 5% ethanol extract of P. niruri and additives such as ethanol 96%, propylene glycol, menthol, DMDM ​​hydantoin, sodium metabisulfite, and TEA. Tonic preparations applied topically to the skin that has been shaved backs of mice. Observations carried out on hair length on day 7, 14 and 21, while the weight of the hair on the 21st day. Primary skin irritation test performed on 18 animals back skin test.


Keywords

P. niruri L., Hair tonic, Hair growth activity

Cite This Article

Luliana, S., Desnita, R., Rawinda, R. (2018). Formulation of Hair Tonic of Meniran (Phyllanthus niruri L.) Ethanol Extract as Hair Grower in Male White Rat (Rattus norvegicus) Wistar Strain. International Journal for Pharmaceutical Research Scholars (IJPRS), 7(3), 136-145. http://dx.doi.org/10.31638/IJPRS.V7.I3.00065


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