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Synthesis and Spectroscopic Characterization of Novel Hybrid Antibacterial Molecules of Fluorene and Triazole


Received On: 27/12/2016
Accepted On: 05/01/2017


Author(s)

Amol K. Patil, Bharatkumar B. Patel, Kokila A. Parmar


Author's Affiliation

Department of Chemistry, Sheth M. N. Science College, Patan, Gujarat, India.


Abstract

A series of fluorene and triazole hybrids were designed and effectively synthesized through reaction of triazole at fluorene ring. These compounds were thermally and morphologically stable and it shows pharmaceuticals useful as antibacterial material. This multifunctional component to fluorene makes them potential drug candidate for the treatment of various diseases. It is intended to help medicinal chemist in designing and synthesizing novel and potent hybrid compounds for the different disorders. The structural designing of the these fluorene compounds have been made on the basis of their elemental analysis, spectral analysis and other physico chemical investigations, antibacterial activities of the synthesized compounds have been determined qualitatively against different pathogenic bacteria. The structures were confirmed by MASS, 1H NMR, IR and UV spectroscopy.


Keywords

Fluorene, Triazole, Drug, Spectroscopy, Pharmaceuticals, 1H NMR

Cite This Article

Amol K. Patil, Bharatkumar B. Patel, Kokila A. Parmar. (2016). Synthesis and Spectroscopic Characterization of Novel Hybrid Antibacterial Molecules of Fluorene and Triazole, International Journal for Pharmaceutical Research Scholars, 5(4), 147-152.


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