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A study of Nifedipine in the Treatment of Preterm Labor of South Indian Origin

Received On: 11/03/2012
Accepted On: 15/03/2012


Ragunath, M.P., Sasmal, D., Dhanaraj, M.

Author's Affiliation


The first line Treatment of preterm labor at CSI Kalyani hospital Chennai was hydration and bed rest followed by tocolytics, the hospital followed a treatment protocol with nifedipine. A total of 48 patients with singleton pregnancies at a gestational age between 28-36 weeks were selected according to the protocol to receive nifedipine. The meta-analysis showed similarities with respect to the age at preterm labor, a status of gravid, suppression of preterm labor, prolongation of pregnancies, adverse events, neonatal outcomes by apgar scores. The results confirmed that nifedipine is a growing calcium channel blocker as a safe and potential drug in the treatment of preterm labor especially in situations where a woman needs a full course of corticosteroids for fetal lung maturation or transfer to the hospital that can provide neonatal intensive care.


Nifedipine, Preterm labor, Tocolytics

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