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Synthesis, Identification and Antimicrobial Activity of Some Novel Quinazolinone Derivatives and its Metal Complexes


Received On: 02/01/2015
Accepted On: 07/01/2015


Author(s)

Mamtora, M.J., Mahetar, J.G., Manavar, R.B., Jadeja, J.J., Shah, M.K.


Author's Affiliation


Abstract

In the present study O, N, O-donating ligand was prepared from the condensation of 2-aminobenzohydrazide and o-vanillin. The chemical structures were confirmed by Mass, ESI Mass, IR, 1H NMR, 13C NMR spectroscopy and Elemental analysis. Metal complex of this ligand is neither air- nor moisture-sensitive. The compounds were tested antimicrobial activity against the four bacterial and four fungal strains. The metal complexes display effective inhibitory action than ligand against test organisms.


Keywords

Dihydroquinazolinone, Schiff Base, Metal Complexes, Antimicrobial Activity

Cite This Article

Mamtora, M.J., Mahetar, J.G., Manavar, R.B., Jadeja, J.J., Shah, M.K. (2015). Synthesis, Identification and Antimicrobial Activity of Some Novel Quinazolinone Derivatives and its Metal Complexes, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(1), 38-44.


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