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Synthetic Advances and Biological Activities of 4-Hydroxy Coumarin Derivatives


Received On: 24/11/2013
Accepted On: 27/11/2013


Author(s)

Karia, D. C., Pancholi, K. S., Varu, R. A.


Author's Affiliation


Abstract

Synthesis of a series of 4-hydroxy-6-methyl-3-(substituted methyl)-2H-chromen-2-one. (4a-g) was achieved from different secondary amine, formaldehyde and 4-hydroxy-6-methyl-2H-chromen-2-one using Con HCl added and refluxed within 8 hrs with good yield. The structures of the products were supported by FTIR, PMR and mass spectral data.


Keywords

4-hydroxy-6-methyl-3-(substituted methyl)-2H-chromen-2-one; secondary amine, 2-Aformaldehyde, only refluxed

Cite This Article

Karia, D. C., Pancholi, K. S., & Varu, R. A. (2013). Synthetic Advances and Biological Activities of 4-Hydroxy Coumarin Derivatives. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(4), 139-142.


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