Abstract

Given the resistance of bacteria against molecules available for the treatment of infectious diseases, the search for new molecules is required. The answer to this call has led to the evaluation of the antibacterial activity of Terminalia Mantaly on the in vitro growth of Pseudomonas aeruginosa ATCC 27863 and hospital isolate of Pseudomonas aeruginosa. In fact, eight extracts are prepared from this specie plant: two crude extracts (aqueous and hydro-ethanol) and six extracts from liquid/ liquid partition of the hydro-ethanol extract. Those extracts were tested. Studies by the diffusion method in solid medium and the method of double dilution in liquid medium revealed that the extracts have an inhibitory activity on the germs studied. Of all extracts, M₁₂ aqueous phase of the hexane-water partition presented the best activity. The diameters are 19 ± 0.57 mm inhibitions against Pseudomonas aeruginosa ATCC 27863 and 14 ± 1 mm on the clinical isolate. The minimum inhibitory concentrations (MIC) are 312.5 µg / ml and 1250 µg / ml respectively on these bacterial germs.

Keywords

Terminalia Mantaly, Pseudomonas Aeruginosa, Antibacterial Activity

Cite This Article

Jaab, A., Kokora, A. P., Yaye, Y. G., Bahi, C., Loukou, Y. G., Coulibaly, A., & Djaman, A. J. (2014). Action Spectrum of Terminalia Mantaly on the In Vitro Growth of Pseudomonas Aeruginosa. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(1), 795-800.