Abstract

Leea rubra has been used as a Lanna Traditional Medicines for Mahoog.  In this study, the antibacterial and antioxidant activities of crude ethanol extract and its different solvent fractions of the L. rubra were evaluated (namely Hexane fraction (HF), ethylacetate fraction (EF) and water fraction (WF). The antibacterial activities on 4 strains of microorganisms i.e. Staphylococcus aureus ATCC 25923, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 9027 were carried out by using agar diffusion technique and the antioxidant activities were determined by using 2,2´-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) free radical scavenging assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and ferric reducing antioxidant power (FRAP) assay.  Among the different fractions, the EF fraction exhibited higher antibacterial activity against gram-positive and antioxidant activity than the other fractions.  Thus, the results suggest that L. rubra is a potential source of antibacterial and antioxidants and could serve as the base for drug development.

Keywords

Leea rubra, Antioxidant Activity, Antibacterial Activity

Cite This Article

Kadchumsang, S., Panee, S. A., Sookkhee, S., Chansakaow, S. (2014). Antibacterial and Antioxidant Activities of Crude Ethanolic Extract and Solvent Fractions of Leea rubra Stems. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(2), 622-626.