Abstract

Biomarkers are biological measures of a biological state and play an important role in understanding the relationships between exposure to environment, the development of chronic diseases and identification of subgroups that are at increased risk for disease. The importance of biomarkers has increased tremendously because of its ability to understand the whole spectrum of disease process. Many biomarkers with potential clinical value are been developed and identified by advances in high-throughput technology. Tracking the complex pathophysiology involved in disease is possible with extensive studies of genomics, proteomics, metabolomics and transcriptomics. Along with molecular biomarkers now imaging biomarkers are gaining importance, offering earlier detection of some diseases than molecular markers and enabling practitioners to see into the body without the need for invasive procedures. In this review we summarize a comprehensive literature on biomarkers with emphasis on the development and applications of biomarkers.

Keywords

Biomarkers, High-Throughput Technology, Proteomics, Genomics, Transcriptomics, Metabolomics, Imaging Biomarkers

Cite This Article

Bagde, A.S., Kadam, V.J., Khanvilkar, V.V., Kothekar, R.R. (2015). Biomarkers: A Review, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(3), 66-77.