Abstract

The main obejcetive of this study is to synthesize 2-(substituted phenyl)-3-[{4-(1-naphthyl)-1, 3-thiazol-2-yl} amino]-5-methyl-1, 3-thiazolidin-4-ones (TM₁-TM₁₀) from 1-acetyl naphthalene. The synthesized compound, characterized on the basis of satisfactory analytical and spectral (IR, H¹NMR, Mass) data, have shown moderate to good antidiabetic activity.

Keywords

Antihyperglycemic activity, 1-Acetylnaphthalene, Thiazoles, Thiazolidinones

Cite This Article

Ahmed, O., Salahuddin, M. D., Vinutha, K., & Sharma, P. (2013). Design, Synthesis and Biological Evaluation of Some Novel Substituted Thiazolidinone Derivatives as Potent Antihyperglycemic Agents. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(3), 166-173.