Abstract

Cordia Africana Lam. is a well known traditional ethnomedicinal use in the treatment of many diseases among African especially the South-east people of Ethiopia. The present study was undertaken to investigate the in vitro antioxidant value of aqueous, benzene, CCl₄ and hexane extracts of leaves, stem and fruits of C.africana along with finding its phytochemicals screening. In vitro antioxidant actions of plant extract was analyzed by measuring its total flavonoid, total phenol, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing property. The preliminary phytochemical analysis was carried out on extract based on the standard prescribed method. The results of phytochemical analyses showed the presence of alkaloids, flavonoids, total phenols and tannins. The total phenol and flavonoid contents are 224.78mg gallic acid equivalent/g extract and 335.45mgQuercetin equivalent/g extract respectively. The extracts exhibited significantly high and dose-dependent DPPH radical scavenging and ferric reducing property similar with the respective standards, Quercetin and Ascorbic acid. Established along the present findings, C.africana of whole plant possess a noteworthy antioxidant potential and could be shown evidence of as a source of antioxidant additives.

Keywords

Cordia Africana, Preliminary Phytochemical Analysis, In Vitro Antioxidant Activity

Cite This Article

Kumar, G., Letha, N., Nair, S. P., Gani, S. B. (2015). Evaluation of Phytochemical Screening and In Vitro Antioxidant Activity of Cordia Africana Lam. (Family: Boraginaceae), A Native African Herb, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(4), 188-196.