Received On: 30/04/2019
Accepted On: 01/06/2019
Basudev Sahana, Kuhu Bhaduri
Department of Pharmaceutics, Institute of Pharmacy, Jalpaiguri, Dept. of Health and Family Welfare, Govt. of West Bengal, India
Polymer is a large molecule made by linking many monomers together. A wide variety of polymers have been discovered with the great efforts of polymers scientists. Polymers are the backbone of pharmaceutical formulation design and development for both the conventional and controlled release drug delivery systems. Varieties of polymers have been utilized in pharmaceutical product development for their appreciate biodegradable, biocompatible and mucoadhesive characteristics. The chemical characteristics of polymers depend on the chemistry of their monomer units and nature of the link between two monomers. Most of the pharmaceutical formulations have been devised based on the polymeric materials. The present study is highlighting the polymeric substances with specific properties such as solubility, sensitivity, biodegradability, biocompatibility, antigenicity, film forming nature, mucoadhesiveness etc. and their utilization in pharmaceutical formulation development, drug carrier activity, mucoadhesive formulations, food industries, dairy and meat products and tissue engineering fields. The biodegradable, biocompatible and mucoadhesive polymers have been specially discussed with their chemistry and pharmaceutical applications as an excellent excipient in controlled release drug delivery systems. The biodegradable polymers poly lactic acid (PLA), poly glycolic acid (PGA) and their conjugate poly lactide co glycolic acid (PLGA) (85:15) based parenterally administrable nanoparticles containing anti cancer drug tamoxifen citrate as depot formulations for long term activity has been specially highlighted in this article.
Controlled Release, Nanoparticles, Depot, Mucoadhesive, biodegradable, PLGA.
Cite This Article
Basudev Sahana, Kuhu Bhaduri. (2019). Polymers: Excellent Formulations Devising Agent. International Journal for Pharmaceutical Research Scholars, 8(2); 1-15.