IJPRS

Home Abstract

Polymers: Excellent Formulations Devising Agent


Received On: 30/04/2019
Accepted On: 01/06/2019


Author(s)

Basudev Sahana, Kuhu Bhaduri


Author's Affiliation

Department of Pharmaceutics, Institute of Pharmacy, Jalpaiguri, Dept. of Health and Family Welfare, Govt. of West Bengal, India


Abstract

Polymer is a large molecule made by linking many monomers together. A wide variety of polymers have been discovered with the great efforts of polymers scientists. Polymers are the backbone of pharmaceutical formulation design and development for both the conventional and controlled release drug delivery systems. Varieties of polymers have been utilized in pharmaceutical product development for their appreciate biodegradable, biocompatible and mucoadhesive characteristics. The chemical characteristics of polymers depend on the chemistry of their monomer units and nature of the link between two monomers. Most of the pharmaceutical formulations have been devised based on the polymeric materials. The present study is highlighting the polymeric substances with specific properties such as solubility, sensitivity, biodegradability, biocompatibility, antigenicity, film forming nature, mucoadhesiveness etc. and their utilization in pharmaceutical formulation development, drug carrier activity, mucoadhesive formulations, food industries, dairy and meat products and tissue engineering fields. The biodegradable, biocompatible and mucoadhesive polymers have been specially discussed with their chemistry and pharmaceutical applications as an excellent excipient in controlled release drug delivery systems. The biodegradable polymers poly lactic acid (PLA), poly glycolic acid (PGA) and their conjugate poly lactide co glycolic acid (PLGA) (85:15) based parenterally administrable nanoparticles containing anti cancer drug tamoxifen citrate as depot formulations for long term activity has been specially highlighted in this article.


Keywords

Controlled Release, Nanoparticles, Depot, Mucoadhesive, biodegradable, PLGA.

Cite This Article

Basudev Sahana, Kuhu Bhaduri. (2019). Polymers: Excellent Formulations Devising Agent. International Journal for Pharmaceutical Research Scholars, 8(2); 1-15.


Recent Articles

Get FREE Updates for Upcoming
Pharma News, Jobs & Conferences

You have successfully subscribed to the newsletter

There was an error while trying to send your request. Please try again.

IJPRS will use the information you provide on this form to be in touch with you and to provide updates and marketing.