Antioxidant and Anticancer Activity of Asparagus racemosus on MCF-7 Cell line

Author(s)

Selvan, C. T., Velavan, S., Milton, M. C. J.

Author's Affiliation

Abstract

To investigate the in vitro antioxidant and anticancer activity of Asparagus racemosus rhizome on MCF-7 Cell line. Phytochemicals of methanol and aqueous extract of Asparagus racemosus were analysed by using standard methods. In Vitro antioxidant studies were carried out for the methanol extracts of the Asparagus racemosus using various free radical models such a DPPH, Reducing power assay and Hydrogen peroxide scavenging assay. In vitro cytotoxic assay such MTT assays were carried out in methanolic extract against EAC cell line.  The results of the present study demonstrated that the qualitative phytochemical analysis of the methanol and aqueous extract of Asparagus racemosus showed the presence of alkaloids, tannin, flavonoids, saponin, glycosides, and phenolic compounds. The antioxidant activity of methanolic extract of rhizome Asparagus racemosus confirmed by free radical scavenging activity and reducing (FRAP) and it was found to be significant. The result revealed that the methanolic extract of Asparagus racemosus showed pronounced anticancer activity against MCF-7cell line. It revealed that the crude methanolic extract of Asparagus racemosus has anticell proliferative activity against MCF-7 cell lines. From our study it is concluded that, the phytochemicals present in the Asparagus racemosus possess antioxidant and anticancer activity.

Keywords

Asparagus Racemosus, Phytochemicals, Antioxidant, Anticancer

Cite This Article

Selvan, C. T., Velavan, S., & Milton, M. C. J. (2014). Antioxidant and Anticancer Activity of Asparagus racemosus on MCF-7 Cell line. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(3), 315-321.