Patel, P., Patel P.U.
This method has been developed by measuring the absorbance of Gemcitabine HCL at 254 nm (pH 3.0 – 10.9). The method is simple, accurate and precise, giving linearity in the range of 14 – 34 μg/mL for Gemcitabine HCL with R2= 0.999 (n= 6). The method was employed in testing the concentration of Gemcitabine HCL in marketed formulations, and the results were found in agreement with the labeled amount.
UV spectrophotometry, Isosbestic point, pH independent, Gemcitabine HCL
Cite This Article
Patel, P., Patel P.U. (2017). Development and Validation of pH-Independent Spectroscopic Method for Estimation of Gemcitabine HCl in Pharmaceutical Formulation. , 6(2), 140 - 145.