Disintegration Controlled Matrix Tablet: A Review

Author(s)

Deokate, U.A., Wavhale, J.L.

Author's Affiliation

Abstract

A number of technologies are available to control or modify the drug release from a dosage form. Mostly are of oral dosage form and they are categorized as matrix, reservoir or osmotic system. This review focused on the Disintegration Controlled Matrix tablet (DCMT) formulation development. The solid dispersion containing water soluble matrix forming agent, disintegrating agent, and wax mainly produce the DCMT system. With the help of the DCMT drug release can be sustained up-to 24Hrs. This dosage form gives the increase in the solubility and bioavailability of the drug. For drugs having low solubility DCMT is the novel approach for sustain release formulation.

Keywords

Disintegration Controlled Matrix Tablet (DCMT), Solid Dispersion, Wax, Disintegrating Agent, Matrix Forming Agent

Cite This Article

Deokate, U.A., Wavhale, J.L. (2015). Disintegration Controlled Matrix Tablet: A Review, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 411-416.