Vats, S., Saxena, C., Easwari, T.S., Shukla, V. K.
These modern days there is an upsurge in topical formulations such that it can be prepared by varying physico-chemical properties and providing better localized action. The patient adherence to topical formulations is significant in relation to chronic skin diseases, like fungal infections, acne, psoriasis. Emulgel is one of the recent technology in NDDS used topically having characteristics of dual control release i.e. emulsion as well as gel. Despite of many advantages of gels there is a major limitation of delivering the hydrophobic drug. Henceforth emulgel has been emerged as an auspicious topical drug delivery system for hydrophobic drugs and proves a boon for dermal care and cosmetology. It is prepared by different polymers which work as an emulsifier and thickener because the gelling capacity of these compounds give rise to stable emulsions and creams by decreasing surface and interfacial tension while at the same time increasing the viscosity of the aqueous phase. Emulgel are having major advantages on novel vesicular systems as well as on conventional systems considering various aspects. Numerous permeation enhancers can potentiate the effect of decreasing skin barrier resistance on the other hand promoting solubility of the drug in vehicle is also feasible. The use of emulgels can be considered well in analgesics and antifungal drugs.
Emulgel, Cosmetology, Hydrophobic Drug, Polymer, Chronic Skin Diseases
Cite This Article
Vats, S., Saxena, C., Easwari, T.S., & Shukla, V.K. (2014). Emulsion Based Gel Technique: Novel Approach for Enhancing Topical Drug Delivery of Hydrophobic Drugs. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(2), 649-660.