Evaluation of Anti Ulcer Activity of Cordia Monoica Roxb Stem

Author(s)

Ramana, K. V., Trivedi, M. H., Reddy, P. R. K., Rao, C. V.

Author's Affiliation

Abstract

Cordia monoica Roxb belongs to family Boraginaceae. It is fairly common in south India. It is a small tree with white flowers and yellow fruits. In the present study an attempt has been made to evaluate the anti ulcer activity of the chloroform, ethyl acetate and methanol extracts of the stems of the Cordia monoica Roxb. Acute toxicity studies were performed as per OECD-423 guidelines. Toxicity signs and symptoms were not observed. 80% ethanol was used as inducing agent for ulcer. The extracts showed significant anti ulcer activity when compared with standard Lansoprazole (30 mg/ kg). This study suggested that, Cordia monoica possess anti ulcer activity.

Keywords

Cordia monoica, Boraginaceae, anti- ulcer activity, 80% ethanol, toxicity, Lansoprazole

Cite This Article

Ramana, K. V., Trivedi, M. H., Reddy, P. R. K., & Rao, C. V. (2013). Evaluation of Anti Ulcer Activity of Cordia Monoica Roxb Stem. International Journal for Pharmaceutical Research Scholars, 2(4), 300-302.