GC-HS Method Development for the Estimation of Benzene Content in Lovastatin

Author(s)

Patel, D., Chauhan, K., Parmar, Y., Patel, S., Sannigrahi, P.

Author's Affiliation

Abstract

A  simple,  fast  and  accurate  method  has  been  developed  for  the  estimation of  benzene content  in  Lovastatin  by  Gas  Chromatography.  The analysis was carried out on Perkin Elmer Clarus 600 GC-HS Chromatograph. The column used was DB-624 30m X 0.32 mm X 1.8 µm fused silica analytical column (6%  cyanopropylphenyl  94 %  dimethylpolysiloxane  as  a stationary  phase).The  detector  used  was  FID  detector.

Keywords

Gas Chromatography, Lovastatin, Benzene

Cite This Article

Patel, D., Chauhan, K., Parmar, Y., Patel, S., Sannigrahi, P., Belwal, C., Vardhan, A. (2013). GC-HS Method Development for the Estimation of Benzene Content in Lovastatin. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(2), 140-145.