Hypoglycemic and Hypolipidemic Effect of Aegle marmelos Leaf Extract in Alloxan Induced Diabetic Male Albino Rats

Author(s)

Rajalakshmi, A., Senthilkumar, B., Devi, K.

Author's Affiliation

Abstract

Aegle marmelos is used extensively in the indigenous system of medicine as an anti-diabetic agent. The current investigation focuses on the serum insulin augmentation, anti-hyperglycemic and anti-hyperlipidemic property of aqueous leaf extract of Aegle marmelos on alloxan induced diabetic male albino rats. The diabetes induced animals were fed with the leaf extract at 250mg/kg body wt and 350mg/kg body wt. The aqueous leaf extract administrated animals revealed a significant increment of serum insulin levels, higher reduction in hyperglycemia and hyperlipidemia when compared to the diabetic control rats. These results further suggest that Aegle marmelos may be useful in the therapy and management of hyperglycemia by reducing blood glucose and hyperlipidemia by reducing lipid levels.

Keywords

Aegle marmelos, Alloxan, Hyperglycemia, Hyperlipidemia

Cite This Article

Rajalakshmi, A., Senthilkumar, B., & Devi, K. (2013). Hypoglycemic and Hypolipidemic Effect of Aegle marmelos Leaf Extract in Alloxan Induced Diabetic Male Albino Rats. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(4), 88-93.