Novel Therapeutic Approaches to a Chronic Inflammatory Disorder – Asthma

Author(s)

Talath, F., Osman, A., Afiya, A., Amatullah, F., Mahboob, A.

Author's Affiliation

Abstract

Asthma is a chronic inflammatory disease of respiratory tract that attacks more than 300 million people all over the world. It is gradually identified that larger percentage of patients suffering from asthma persists terribly governed with severe exacerbations inspite of giving conventional treatments by inhaled corticosteroids or even by various other agents. The evolution of various therapies and therapeutic agents has shown a greater response in treating severe asthma. This review focuses upon the various proceeding therapeutic approaches in treating this chronic inflammatory airway disease. Asthma is a respiratory disease that causes the uncertain and reversible obstruction of airflow and may also cause bronchospasm. The symptoms in the patient may include continuous coughing, breathing audibly, pain in the chest, difficulty in breathing. This chronic disease is a union of various environmental and genetic factors. This may also become chronic in young children and infants. This may be due to the background of pneumonia, bronchitis or diligent cough along with cold. The pathophysiology of asthma is a complicated one and involves the inflammation in the airways, obstruction of airflow, hyper responsiveness of bronchi etc. Diagnosis may include Spirometry accompanied by post bronchodilating response as the main test for confirmation of asthma. Other test may also include radiography of chests etc., which may help in the detection of severe symptoms of asthma. The therapeutic approach may include Anti-IgE therapy, Anti IL-5 therapy, thermal bronchoplasty, Antifungal therapy etc. These are considered to be the novel therapies in the treatment of asthma. The present study based on providing better therapies in the treatment of chronic disorder, Asthma.

Keywords

Chronic, Inhaled Corticosteroids, Bronchospasm, Spirometry, Anti IL-5 Therapy

Cite This Article

Talath, F., Osman, A., Afiya, A., Amatullah, F., Mahboob, A. (2015). Novel Therapeutic Approaches to a Chronic Inflammatory Disorder - Asthma, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(3), 112-117.