Dubey, A.K., Rajagopala, S., Patel, K.S., Harisha, C.R., Shukla, V.J.
The present work was carried out to standardize the finished product Vyaaghreeharetakee Avaleha to confirm its identity, quality, and purity. The two major ingredients of the formulation are Vyaaghree (Solanum xanthocarpum Schrad. & Wendl.) and Haretakee (Terminalia chebula Ritz.). The formulation is widely indicated for the management of Kaasa (Cough), Swaasa (breatlessness) due to Tamak Shwaasa (Bronchial Asthma). Due to various types of side-effect of available chemical formulations to suppress the condition, there has been a worldwide demand of herbal formulations. But quality and purity without side effect is a big concern. Thus the finished products of herbal preparation in the form of Vyaaghreeharetakee Avaleha was tried to standardize. Pharmacognostical and phyto-chemical observations revealed the specific characters of all active constituents used in the preparation. The phytochemical analysis and High Performance Thin Layer Chromatography has also been performed. The drug combination was also characterized for its physico-chemical properties. The presence of microsphenoidal crystals of calcium oxalate, tracheids with irregular walls and bordered pits, mesocarp cells, simple, oval shaped starch grains, stone cells varying in sizes, shapes and thickness, stone cells with broad lumen in groups, Fragment of border pitted vessels, Epicorp-beaker shaped, oil and tannin content and acicular crystal, alureon grains, 1 to 2 rosette crystals, prismatic crystals, and immature pollen grains were the characteristic features observed in the microscopy of drug combination. Phyto-chemical analysis indicated presence of alkaloids, tannins, saponins, flavonoids, glycosides, and Steroid.
Tamak Shwaasa, Bronchial Asthma, Solanum xanthocarpum, Pharmacognosy, Phytochemistry, HPTLC
Cite This Article
Dubey, A.K., Rajagopala, S., Patel, K.S., Harisha, C.R., Shukla, V.J. (2015). Pharmacognostical and Phytochemical Standardization of Vyaaghreeharetakee Avaleha, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 390-396.