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Review Article

Review on Mouth Dissolving Film Technology


Rathod, S., Surve, G. D., Phansekar, M., Bhagwan, A.

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Oral drug delivery is the most widely utilized route of administration. Major drawbacks related to solid oral delivery systems are lower bioavailability, longer onset of time. Also geriatric, pediatric and dysphasic patients have difficulty in swallowing or chewing solid dosage forms. They are unwilling to take solid preparations due to fear of chocking. Even with fast dissolving tablets there is fear of choking due to its tablet type appearance.  Fast dissolving oral films (FDOFs) are the most advanced form of oral solid dosage form due to more flexibility and comfort. It improve the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. In US market the OTC films of pain management and motion sickness are commercialized. More importantly, prescription OTFs have now been approved in US, EU and Japan which are the three major regions. The current review focuses on the recent development in the oral dissolving film and discusses about its technique for preparation of film as well its evaluation.


Mouth Dissolving Film, Film Forming Polymer, Solvent Casting Technique, Disintegration Time, Dissolution Test

Cite This Article

Rathod, S., Surve, G. D., Phansekar, M., & Bhagwan, A. (2014). Review on Mouth Dissolving Film Technology. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(1), 635-647.

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