Synthesis and Characterization of novel 6-[3,5-bis(trifluoromethyl)phenyl]-4-(substitutedphenyl)-1,4-dihydropyrimidin-2-ol

Author(s)

Vyas, T., Vyas, K.

Author's Affiliation

Abstract

Synthesis of various pyrimidines 3(a-o) from (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one and Urea in presence of NaOH. The structures of the synthesized compounds were confirmed on the basis of spectral and elemental analysis.  The synthesized compounds were screened for antimicrobial activity.

Keywords

Chalcones, (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one, urea, dihydropyrimidine-2-ol compounds

Cite This Article

Vyas, T., Vyas, K. (2012). Synthesis and Characterization of novel 6-[3,5-bis(trifluoromethyl)phenyl]-4-(substitutedphenyl)-1,4-dihydropyrimidin-2-ol, International Journal for Pharmaceutical Research Scholars (IJPRS), 1(3), 8-11.