Kothari, P., Desai, H.
Synthesis of a series of 4-(4-(4-(trifluoromethyl)-2-nitrophenoxy)phenyl)-N-(substitutedphenyl) -1,2,3,4-tetrahydro-6-methyl-2-oxopyrimidine-5-carboxamide (4a-j) was completed from 4-(4-(trifluoromethyl)-2-nitrophenoxy)benzaldehyde, N-(substituted phenyl)-3-oxobutanamides and using catalytical amount of Conc. hydrochloric acid in methanol the product obtained was isolated. So to the excellent yield. The structures of the products were supported by FTIR, 1H NMR and mass spectral data.
N-(Substituted phenyl)-3-Oxobutanamides, 4-(4-(Trifluoromethyl)-2-Nitrophenoxy) Benzaldehyde, Conc. HCl, Methanol Only Refluxed
Cite This Article
Kothari, P., & Desai, H. (2016). Synthesis of Plausible Fluoro Containing Pyrimidine Derivatives, International Journal for Pharmaceutical Research Scholars (IJPRS), 5(1), 192-195.