Emulgel: A Novel Approach for Delivery of Hydrophobic Drugs

Author(s)

Ahirrao, S.P., Raut, T.S., Nikam, A.S., Raje, V.V.

Author's Affiliation

Abstract

Most of the drugs are effective by oral, parenteral routes despite of several advantages there are limitation so they are drown back and requires an alternate route of administration like topical, ophthalmic, vaginal. Looking to the better patient compliance topical drug delivery has being growing hastily. Among the various group of semisolid preparation, the use of gel has lengthened both in cosmetics and in the pharmaceuticals. In spite of several advantages of gel there is limitation in delivery of hydrophobic drugs, so to beat this limitation an emulsion base advance is being mostly used. Emulgels are emulsions, either of the oil-in-water or water in oil type, which are gelled by mixing with a gelling agent. Due to presence of oil portion; it leads to more penetration of API in skin. In short Emulgels are the combination of emulsion and gel. The major objective behind this formulation is the delivery of hydrophobic drugs to the systemic circulation via the skin .The emulgels for dermatological use has several favourable properties Such as being thixotropic, greaseless, easily spreadable, easily removable, emollient, non-staining, water-soluble, greater shelf life, bio-friendly, clear and pleasant appearance.

Keywords

Emulgel, Topical Drug Delivery, Penetration Enhancer, Hydrophobic Drug, Emulsifier

Cite This Article

Ahirrao, S.P., Raut, T.S., Nikam, A.S., Raje, V.V. (2015). Emulgel: A Novel Approach for Delivery of Hydrophobic Drugs, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 152-160.