Study on Timely Administration of Antibiotic Prophylaxis Practice in Surgical Procedures at a Tertiary Care Teaching Hospital, South India

Author(s)

Devarajan, K., Koya, J., Paidi, N.R., Rajeswari, R., Sudarshan, P.

Author's Affiliation

Abstract

Surgical site infections (SSI) are an important cause of morbidity and mortality and increased costs in today's health care environment .These events represent the most common nosocomial infections in surgical patients. The overall incidence of SSIs has been reported to be 2% to 5% in patients undergoing clean extra-abdominal procedures and up to 20% for intra-abdominal procedures. We prospectively evaluated the timely administrated antibiotic prophylaxis, in 61 patients who underwent elective 'contaminated' and 'clean contaminated' surgical procedures at tertiary care teaching Hospital in South India between February 2014 to May 2014. Clean, and dirty or infected wound surgeries were excluded in the study. All the cases included in the study were compared with standard American Society of Health-System Pharmacists (ASHP) therapeutic guidelines for antimicrobial prophylaxis in surgical procedures. The administration of antibiotic within 60 minutes before the time of incision is considered as timely administration. The incidence of Post-operative infection is also documented. Of the 61 cases evaluated 16 (26.22%) cases were only administered with antibiotic surgical prophylaxis, of these only 1 case (6%) received timely antimicrobial prophylaxis within 60 minutes before the time of incision as per the guideline. The overall incidence of Post-operative infection was found to be 11.47% in the study site, during the study period. The overall incidence of post-operative infection is less in antimicrobial prophylaxis administered cases when compared to non-administered cases.

Keywords

Antimicrobial Prophylaxis, Surgical Site Infections, Post-Operative Infections, Timely Administration

Cite This Article

Devarajan, K., Koya, J., Paidi, N.R., Rajeswari, R., Sudarshan, P. (2015). Study on Timely Administration of Antibiotic Prophylaxis Practice in Surgical Procedures at a Tertiary Care Teaching Hospital, South India, International Journal for Pharmaceutical Research Scholars (IJPRS), 4(2), 317-321.