Biological and Fluorescence Activity of Newly Synthesized Ni(II) Heterochelates

Author(s)

Patel, A. K., Patel, K. S., Patel, B. D., Patel, K. D.

Author's Affiliation

Abstract

The present work staunch from our interest by the synthesis, characterization and biological evaluation of Ni(II) complexes, which have been synthesized by mixing an aqueous solution of Ni(NO₃)₂ in 1 : 1 molar ratios with ethanolic bidentate ligands (Bromocoumarin derivatives) and ciprofloxacin. Spectral studies confirm ligands to be mono functional bidentate and octahedral environment around metal ions. Thermal behaviour of newly synthesized mixed ligand Ni (II) complexes were investigated by means of electronic spectra and magnetic measurements. Characterization of the ligands has been carried out by elemental analysis, melting point determinations, mass spectra, ¹H NMR, ¹³C NMR, and FT-IR, while structure of metal complexes were investigated and confirmed by FT-IR and FAB-mass spectral studies. Both the ligands as well as its complexes have been screened for their in vitro antimicrobial and fluorescence activities.

Keywords

Ni(II) Complexes, Antimicrobial,  Fluorescence

Cite This Article

Patel, A. K., Patel, K. S., Patel, B. D., & Patel, K. D. (2014). Biological and Fluorescence Activity of Newly Synthesized Ni(II) Heterochelates. International Journal for Pharmaceutical Research Scholars (IJPRS), 3(4), 92-102.