Shaikh, P.V., Brahmbhatt, D.I.
The synthesis of various benzofuranyl pyridinyl and benzofuranyl styryl pyridinyl substituted coumarins has been carried out by reacting 3-cinnamoyl coumarins and 3-(5-arylpenta-2,4-dienoyl)coumarins (coumarin chalcones) with substituted benzofuranoyl methyl pyridinium iodide salts in the presence of ammonium acetate and acetic acid under Krohnke’s reaction condition. The structures of all the synthesized compounds were established on the basis of analytical and spectral data like IR, 1H-NMR, 13C-NMR and mass. The compounds were subjected to in vitro antimicrobial screening against a representative panel of bacteria (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhi) and fungi (Aspergillus niger, Candida albicans).
Coumarins, benzofuranyl pyridine, styryl pyridine, Pyridylcoumarins Kröhnke’s reaction, Antimicrobial activity
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Shaikh, P.V., Brahmbhatt, D.I. (2017). Synthesis, Characterization and Antimicrobial Screening of Some New Benzofuranyl Pyridinyl and Benzofuranyl Styryl Pyridinyl Substituted Coumarins. , 6(1), 116-128.